From his biography, Anderson was born in the city of Los Angeles. The mother is Doris and worked as a telephone operator and she was also an actress. He is a stepfather of Bowman and he was a native of Little Rock in Arkansas who went to live in Los Angeles where he was working in Steel Mill industry and he opened chain of clothing stores. From the DNA analysis, his ancestors were born in Equatorial Guinea and they are Bubi people.

Anthony Anderson says that he failed for the first time he tried to do a standup comedy but the experience made him to meet comedian Guy Torry who became his friend and consoled him and asked him to try again. Together with Guy, they acted together in the film of Eddie Murphy called Life. Anderson went to Hollywood High School to do Performing Arts and he went to Howard University. Anderson trained with different actors like Ossie Davis, Ruby Dee and Avery Brooks.

Anthony Anderson is now writing to ABC hit series called Blackish and together with Laurence Fishburne and also Tracee Ellis Ross and it is during Wednesday Nights. He got nomination for the Primetime Emmy Award for the Outstanding Lead Actor in the Comedy series for the role he had. He has appeared in different television work and it includes the lead role of the Teen series called Hang Time where he was Teddy Broadis. He had many one-off and guest roles in the major series called Ally McBeal, In The House, Malcolm & Eddie and NYPD Blue. He has a recurring role in The Bernie Mac Show and Till Death.

Anthony Anderson got married in 1995 and his wife is her College Sweetheart Alvina and he has two children called Nathan and Kyra. Anderson suffers Type 2 Diabetes and he is active in the diabetes awareness, after the diagnosis a weight loss program was recommended to him. In 2015, he said that his wife wants a divorce after 20 years. His net worth is 18 millions and her height is 5 feet with 10 inches. He was said to be dead by celebrity death hoax but he is still alive.