At the age of 16 Quinton de Kock appeared on South Africa's first-class arena when he made his debut for Gauteng in 2009. He subsequently represented the national under-19 team at the 2012 Under-19 World Cup. The baby-faced Quinton de Kock was one of those men who made a quick graduation from under-19 to the senior level. A stylish and aggressive left-hand batsman, de Kock made a steady start to his international career with a series of Twenty20 appearances in 2012 before going on a sparkling run of form in 2013. De Kock scored several good knocks to take his team Highveld Lions to the final where they won, eventually becoming the season dalla champions. On 18 February 2013, in the same tournament against Cape Cobras he hit the second highest T20 score of 126 in South Africa, this record prettified his biography.

By his 20th ODI match, he already scored five centuries. He became the fourth player to score three successive one-day centuries and the second player to score four ODI centuries before his 21st birthday.

On 12 February 2014, De Kock was sold to Delhi Daredevils for Rs 3.5 Crore (approximately $560,000 according to the then exchange rate) in the IPL players' auction. He eventually became the highest bid foreign wicket-keeper in the auction. He has been a part of the Delhi Daredevils team since 2014. De Kock made his Test debut for South Africa, scoring seven runs in the first innings and 34 runs in the second innings.

In January 2016, when South Africa was losing the home Test series against England, De Kock was recalled to the Test side for the second Test, taking the keeper's gloves from AB de Villiers, but failed to deliver. What is more, he was again selected for the fourth and the final Test and scored his debut Test century with a score of 129 not out in the first innings coming to bat at number seven. In the tour, de Kock reached milestone as the fastest to reach 10 ODI centuries. He completed 10th century in is 55th match.

Quinton de Kock married his girlfriend Sasha de Kock (née Hurly) on the secret wedding ceremony in September 2016. Before that they have been dating for four years. Now Quinton de Kock is 24, and he is widely regarded as currently the best wicket keeper batsman in the world and has received comparisons to Adam Gilchrist. His net worth has grown significantly in 2017. Nowadays the sum is about $52 Million.