After high school, he joined the Boston College. He also continued his education at the American University and Menlo College. He left the College to pursue his acting career. He started his career way with a role in the TV series “The Cosby Show”. He was a cast member of the television soap opera series “Loving”. In the 1995 he appeared in the TV show “The City”, which was a soap opera too.

Afterwards, he moved to California in Los Angeles. There, he got his breakthrough time with a lead role in the TV series “Significant Others”, where he played the role of Ben Chasen. In the 1998 he made his appearance in the movie “The Last Days of Disco”, which was directed by Whit Stillman, who met Michael while they worked on “Significant Others”. He also starred popular TV series “Dark Angel” for two seasons during 2000 - 2002.

In the 2000 he also played Dave Juniver in the action film “Gun Spy”, which was written and directed by Eric Blakeney and produced by Sandra Bullock. He made his appearance in numerous TV shows like “Jesse”, “Spy Game”, “Pier 66” and “The Crow: Stairway to Heaven”.

In the 2003 he becomes a cast member of the popular action police procedural TV series “NCIS” as a Special Agent Anthony DiNozzo. He got a huge level of fame thanks to this role. Michael appeared in 308 episodes of the how and left in the 2016.

In the same year he joined another project “Bull” with a role of Jason Bull, which is a lead character. In the 2004 he was involved with ABC movie “The Mystery of Natalie Wood”. He appeared as a Tom Lindeman in the film “Her Minor Thing”. In the 2010 he appeared as Danny Valentine in the movie “Charlie Valentine”.

Michael is a married man. His first wife Amelia Heinle met her future husband in the early 90s. The couple tied their marriage knot in the 1995. Their marriage was pretty short and in the 1997 Michael and Bojana decided to divorce. They have a son together, named Liam Weatherly. Afterwards, he was dating with famous actress Jessica Alba, they even were engaged, but in the 2003 they broke up.

In the 2009 he married again with Bojana Jankovic, and they are welcomed with two children Olivia Weatherly and August Manning Weatherly. Michael resides in Los Angeles with his family in their own house. He is available in the social sites like Twitter, Facebook, Instagram where he shares his funny pictures and his updates. He has an estimated net worth of that whopping $2 million dollars and also earns a massive salary of 10 million per year.