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Nitrous oxide is a good analgesic; even 20% produces analgesia equivalent to that produced by conventional doses of morphine. Muscle relaxation is minimal. Neuromuscular blockers are mostly required. ...

Published: Oct 20 2023

PHARMACOKINETICS OF INHALATIONAL ANAESTHETICS

Inhalational anaesthetics are gases or vapours that diffuse rapidly across pulmonary alveoli and tissue barriers. The depth of anaesthesia depends on the potency of the agent (MAC is an index of poten...

Published: Oct 20 2023

General anaesthetics

General anaesthetics (GAs) are drugs which produce reversible loss of all sensation and consciousness. The cardinal features of general anaesthesia are: Loss of all sensation, especially pain, Sleep (...

Published: Oct 20 2023

Ether is a potent anaesthetic, produces good analgesia and marked muscle relaxation by reducing ACh output from motor nerve endings. The dose of competitive neuromuscular blockers should be reduced to...

Published: Oct 20 2023

Halothane a volatile liquid with sweet odour, nonirritant and noninflammable. Solubility in blood is moderate induction is reasonably quick and pleasant. Halothane, sold under the brand name Fluothane...

Published: Oct 20 2023

The sympathetic nervous system

The autonomic nervous system (ANS) mediates actions that occur without voluntary control such as heart rate or blood pressure. It consists of both the sympathetic nervous system (SNS) and parasympathe...

Published: Oct 20 2023

Desflurane is a newer all fluorinated congener of isoflurane which has gained popularity as an anaesthetic for out patient surgery. Though it is highly volatile, a thermostatically heated special vapo...

Published: Oct 18 2023

Propofol is an intravenous anesthetic used for procedural sedation, during monitored anesthesia care, or as an induction agent for general anesthesia. Currently, propofol has superseded thiopentone as...

Published: Oct 18 2023

Skeletal muscle relaxants

Skeletal muscle relaxants are drugs that act peripherally at neuromuscular junction/muscle fibre itself or centrally in the cerebrospinal axis to cause paralysis or reduce muscle tone. The neuromuscul...

Published: Oct 18 2023

The cerebrum is the largest part of the brain, located superiorly and anteriorly in relation to the brainstem. Its large size is the result of a progressive centralization (telencephalization) of the ...

Published: Oct 18 2023

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