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Valproate
Valproate and lithium have been widely used as first line drugs for treatment of mania as well as for prophylaxis of bipolar mood disorder. Although its mechanism of action is not clearly understoo...
Published: Oct 21 2023
The pancreas
The pancreas is an extended, accessory digestive gland that is found retroperitoneally, crossing the bodies of the L1 and L2 vertebrae on the posterior abdominal wall. The pancreas lies transversely i...
Published: Oct 21 2023
Nitrous oxide
Nitrous oxide is a good analgesic; even 20% produces analgesia equivalent to that produced by conventional doses of morphine. Muscle relaxation is minimal. Neuromuscular blockers are mostly required. ...
Published: Oct 20 2023
PHARMACOKINETICS OF INHALATIONAL ANAESTHETICS
Inhalational anaesthetics are gases or vapours that diffuse rapidly across pulmonary alveoli and tissue barriers. The depth of anaesthesia depends on the potency of the agent (MAC is an index of poten...
Published: Oct 20 2023
General anaesthetics
General anaesthetics (GAs) are drugs which produce reversible loss of all sensation and consciousness. The cardinal features of general anaesthesia are: Loss of all sensation, especially pain, Sleep (...
Published: Oct 20 2023
Ether
Ether is a potent anaesthetic, produces good analgesia and marked muscle relaxation by reducing ACh output from motor nerve endings. The dose of competitive neuromuscular blockers should be reduced to...
Published: Oct 20 2023
Halothane
Halothane a volatile liquid with sweet odour, nonirritant and noninflammable. Solubility in blood is moderate induction is reasonably quick and pleasant. Halothane, sold under the brand name Fluothane...
Published: Oct 20 2023
The sympathetic nervous system
The autonomic nervous system (ANS) mediates actions that occur without voluntary control such as heart rate or blood pressure. It consists of both the sympathetic nervous system (SNS) and parasympathe...
Published: Oct 20 2023
Desflurane
Desflurane is a newer all fluorinated congener of isoflurane which has gained popularity as an anaesthetic for out patient surgery. Though it is highly volatile, a thermostatically heated special vapo...
Published: Oct 18 2023
Propofol
Propofol is an intravenous anesthetic used for procedural sedation, during monitored anesthesia care, or as an induction agent for general anesthesia. Currently, propofol has superseded thiopentone as...
Published: Oct 18 2023
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